Difficulty swallowing solid foods or liquids.Sudden laughing or crying or displaying angry outbursts for no apparent reason.Increased irritability and forgetfulness.Loss of interest in ordinary pleasurable activities.Changes in judgment, insight, and problem solving.People with PSP often show alterations of mood and behavior. Inability to maintain eye contact during a conversation.Tendency to move the head to look in different directions.Trouble voluntarily shifting gaze vertically (i.e., downward and/or upward).Individuals may have abrupt and unexplained falls without loss of consciousness, a stiff and awkward gait, or slow movement.Īs the disease progresses, most people will begin to develop a blurring of vision and problems controlling eye movement. The most frequent first symptom of PSP is a loss of balance while walking. The pattern of signs and symptoms can be quite different from person to person. PSP affects movement, control of walking (gait) and balance, speech, swallowing, eye movements and vision, mood and behavior, and thinking. Currently there is no effective treatment for PSP, but some symptoms can be managed with medication or other interventions. PSP is different than Parkinson’s disease-another movement disorder-although they share some symptoms (see section, “How is PSP different from Parkinson’s Disease?”). The disorder’s long name indicates that the disease worsens ( progressive) and causes weakness ( palsy) by damaging certain parts of the brain above nerve cell clusters called nuclei ( supranuclear) that control eye movements. It results from damage to nerve cells in the brain that control thinking and body movement. Progressive supranuclear palsy (PSP) is a rare brain disorder that causes problems with movement, walking and balance, and eye movement. How is PSP different from Parkinson's disease?
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